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Canada-0-ENVIRONMENTAL ECOLOGICAL PRODUCTS företaget Kataloger
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Företag Nyheter:
- Systematic characterization of cancer transcriptome at . . .
Unannotated transcripts are closely associated with cancer-related hallmarks and show clinical significance We build a high-confidence RNA binding protein (RBP)-transcript regulatory network, wherein most RBPs tend to regulate transcripts involved in cell proliferation
- Systematic characterization of cancer transcriptome at . . .
Unannotated transcripts are closely associated with cancer-related hallmarks and show clinical sig-ni cance We build a high-condence RNA binding protein (RBP)-transcript regulatory
- Non-coding antisense transcripts: fine regulation of gene . . .
Our main goal is to exemplify antisense transcripts in cancer, with particular emphasis on those acting as microRNA (miRNA) sponges and their role in cancer aggressiveness, metabolism, response to chemotherapy and the epithelial-mesenchymal transition (EMT) miRNA sponges are lncRNAs shown to regulate gene expression through direct binding of
- The landscape of cryptic antisense transcription in human . . .
Applying a robust computational pipeline to publicly available transcriptome and epigenome datasets, we identified hundreds of previously unannotated cryptic antisense polyadenylated transcripts (CAPTs) that were enriched in tumor samples
- RNA splicing junction landscape reveals abundant tumor . . .
We identified 29,051 tumor-specific transcripts (TSTs) in pan-cancer, with a majority of these TSTs being unannotated Our findings show that TSTs are positively correlated with tumor stemness and linked to unfavorable outcomes in cancer patients
- Transcriptomics and solid tumors: The next frontier in . . .
Transcriptomics, which encompasses assessments of alternative splicing and alternative polyadenylation, identification of fusion transcripts, explorations of noncoding RNAs, transcript annotation, and discovery of novel transcripts, is a valuable tool for understanding cancer mechanisms and identifying biomarkers
- Reference-free inferring of transcriptomic events in cancer . . .
Our results suggest that esophageal cancer (ESCA) and glioblastoma processes can be explained via pathogenic microbial RNA, repeated sequences, novel splicing variants, and long intergenic non-coding RNAs (lincRNAs)
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