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- GitHub - bulik ldsc: LD Score Regression (LDSC)
ldsc is a command line tool for estimating heritability and genetic correlation from GWAS summary statistics ldsc also computes LD Scores
- Home · bulik ldsc Wiki - GitHub
Welcome to the ldsc wiki This is the main repository for LD Score documentation If you're just starting to use LD Score, the tutorials on LD Scores; heritability, genetic correlation and the LD Score regression intercept; and partitioned h 2 describe how to run ldsc The FAQ answers several common questions about ldsc output
- LD Score Estimation Tutorial · bulik ldsc Wiki - GitHub
This tutorial describes how to use ldsc to estimate LD Scores from plink format bed bim fam filesets If you are interested in estimating genetic correlation or the LD Score regression intercept from European-ancestry GWAS data, you can download suitable pre-computed LD Scores from this URL; there is no need to compute your own LD Scores
- Heritability and Genetic Correlation · bulik ldsc Wiki - GitHub
By default, the --h2 and --rg flags in ldsc output observed scale heritability To convert to the liability scale, we need to tell ldsc the sample and population prevalence for each trait using the --samp-prev and --pop-prev flags, respectively The population prevalence of scz and bip are both around 1%, and the sample prevalence in each of
- abdenlab ldsc-python3: LD Score Regression (LDSC) - GitHub
LDSC (LD Score Regression) is a command-line tool for estimating heritability and genetic correlation from GWAS summary statistics It also computes LD Scores This tool is essential for researchers in genetics and genomics aiming to understand the genetic architecture of complex traits
- GitHub - mglev1n ldscr: LD Score Regression in R
ldsc_rg() can be used to estimate cross-trait genetic correlations between two or more traits
- FAQ · bulik ldsc Wiki - GitHub
LD Score Regression (LDSC) Contribute to bulik ldsc development by creating an account on GitHub
- kaizhang LDSC - GitHub
This is a computational pipeline to perform the LD Score Regression (LDSC) analysis For more information, see here: https: github com bulik ldsc If you use this pipeline in your paper, Please cit the original publications: https: github com bulik ldsc#citation
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