- The clinical implications of selective IgA deficiency - PMC
Selective IgA deficiency is the most common primary immunodeficiency • It is associated with an increased risk of infections, allergic and autoimmune diseases, and rarely, malignancy • There is a risk of transfusion reactions due to the rare development of IgE against IgA in blood products •
- The clinical implications of selective IgA deficiency - PubMed
Clinical complications include increased risk of sinopulmonary infections with bacteria and viruses, gastrointestinal infections with a predilection for Giardia lamblia, a myriad of autoimmune diseases including systemic lupus erythematosus, hyper- and hypo-thyroidism, Type 1 diabetes, celiac disease, and rarely, malignancy SIgAD must be
- Selective IgA Deficiency - MD Searchlight
Gastrointestinal infections: IgA deficiency can increase the risk of developing giardiasis, an infection caused by a parasite called Giardia lamblia Manifestations include chronic diarrhea, impaired nutrient absorption, and increased nodular lymphoid structures in the gut
- (PDF) Selective IgA Deficiency: Epidemiology, Pathogenesis . . .
Giardia lamblia as gastrointestinal disorders has been Another condition characterized by deficient IgA production and increased risk of respiratory infections is Selective IgA Deficiency
- Selective Immunoglobulin A Deficiency - an overview . . .
Selective IgA deficiency is the most common primary immunodeficiency • It is associated with an increased risk of infections, allergic and autoimmune diseases, and rarely, malignancy • There is a risk of transfusion reactions due to the rare development of IgE against IgA in blood products •
- Selective IgA Deficiency - Picmonic
Selective IgA Deficiency Selective IgA deficiency is a congenital B-cell immunodeficiency, which is often asymptomatic, but can result in recurrent minor infections, diarrhea, and anaphylaxis in the most severe of cases It results from an inability to class switch to IgA, thus limiting the amount of specific IgA that can be produced Because IgA
- Gastrointestinal Manifestations and Complications of Primary . . .
Infections causing chronic diarrhea, commonly related to Giardia lamblia, occur with increased frequency 4 because lack of secretory IgA in sIgAD allows for attachment and proliferation of organisms on the intestinal epithelium 7 G lamblia cysts give rise to trophozoites that colonize the small intestine and trigger bloating, cramping
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